sickle-cell anemia

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Definition

Noun: A serious, inherited blood disorder where the body produces red blood cells that are abnormally shaped like a crescent or sickle. These misshapen cells are rigid and sticky, blocking blood flow and causing pain, organ damage, and a shortage of healthy red blood cells (anemia).

Usage

The term is used as a medical condition noun. It is typically non-countable when referring to the disease in general, but can be countable when referring to specific cases or types. * Sickle-cell anemia is most common in people with ancestry from regions where malaria is or was common. * Early diagnosis is crucial for managing sickle-cell anemia. * The patient was hospitalized due to a complication from his sickle-cell anemia.

Examples
  • Research into new treatments for sickle-cell anemia has advanced significantly.
  • Painful episodes, known as crises, are a hallmark symptom of sickle-cell anemia.
  • She has lived with sickle-cell anemia since birth.
Advanced Usage
  • Sickle-cell anemia is an autosomal recessive genetic disorder, meaning a child must inherit the gene from both parents.
  • The term is often used in public health contexts discussing genetic screening, healthcare disparities, and chronic disease management.
Variants and Related Words
  • Sickle-cell disease (SCD): A broader term that encompasses all disorders related to sickle hemoglobin, including sickle-cell anemia (the most severe form).
  • Sickle-cell trait: The condition of carrying one copy of the altered gene. Individuals with the trait do not have the disease but can pass the gene to their children.
  • Sickling: The process by which red blood cells become sickle-shaped.
  • Sickle-cell crisis: A painful episode that is a common complication of the disease.
Synonyms
  • Sickle-cell disorder
  • Hemoglobin SS disease (HbSS) (This is the specific technical name for the most common type of sickle-cell anemia.)
Related Phrases
  • To be diagnosed with sickle-cell anemia
  • To manage/treat sickle-cell anemia
  • A complication of sickle-cell anemia
  • A carrier of the sickle-cell trait
Noun
  1. a congenital form of anemia occurring mostly in blacks; characterized by abnormal blood cells having a crescent shape

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